What is it?
Coriolus (Coriolus versicolor) is a mushroom. It contains polysaccharide peptide (PSP) and polysaccharide krestin (PSK), which are used as medicine.
Coriolus mushroom grows on stumps and the decomposing wood of trees. The PSP and PSK in coriolus mushroom might help slow cancer growth and boost the immune system.
People use coriolus mushroom to improve response to cancer medicines and radiation. It is also used for muscle strength, fatigue, UTIs, and many other conditions, but there is no good scientific evidence to support these uses.
Possibly Effective for …
- Cancer. Taking polysaccharide krestin (PSK), a substance found in coriolus mushroom, by mouth might improve the response to chemotherapy by a small amount in some people with certain types of cancer.
There is interest in using coriolus mushroom for a number of other purposes, but there isn’t enough reliable information to say whether it might be helpful.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn’t enough reliable information to know if coriolus mushroom is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Interaction Rating=Moderate Be cautious with this combination.
PSP, a chemical found in coriolus mushroom, might change how quickly cyclophosphamide is removed from the body. This might alter how effective it is, and cause more side effects.
Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates)
Interaction Rating=Minor Be watchful with this combination.
Some medications are changed and broken down by the liver. PSP, a chemical found in coriolus mushroom, might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
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