The following research projects were approved by Susan G. Komen's national Board of Directors for funding, and will be funded once the Grant Agreements between Komen and the Grantee institution(s) are fully-executed. There are 7 types (mechanisms) of grants: Career Catalyst Research (CCR), Graduate Training in Disparities Research (GTDR), Postdoctoral Fellowships (PDF), Komen Scholars Grants (KS), Scientific Advisory Board Grants (SAB), Opportunity Grants (OG), and Sponsored Programs and Partnerships (SPP). For more information on the scientific programs and partnerships that are supported by the Komen Research Program, see here.

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Project Title Investigators Organization State/ Country Affiliate Mechanism
Prioritizing adjuvant targeted therapy for TNBC patients via molecular profiling  Justin Balko,Pharm.D., Ph.D. Vanderbilt University TN Greater Nashville Affiliate CCR Basic and Translational
Targeting epithelial-stromal crosstalk networks in breast cancer  Andrew Beck, M.D. Beth Israel Deaconess Medical Center MA Massachusetts Affiliate CCR Basic and Translational
Characterization and targeted therapy of hormone-refractory breast cancer  Sarat Chandarlapaty, M.D., Ph.D. Memorial Sloan-Kettering Cancer Center NY Greater New York City Affiliate CCR Basic and Translational
Alterated ubiquitin signaling networks regulating breast cancer proliferation  Michael Emanuele, Ph.D. The University of North Carolina at Chapel Hill NC North Carolina Triangle to Coast Affiliate CCR Basic and Translational
How does circulating cholesterol promote breast cancer growth and metastasis?  Emily Gallagher, M.D. Icahn School of Medicine at Mount Sinai NY Greater New York City Affiliate CCR Basic and Translational
Targeted blockade of the inflammatory network in triple-negative breast cancer  Zachary Hartman, Ph.D. Duke University Medical Center NC North Carolina Triangle to Coast Affiliate CCR Basic and Translational
Mitochondrial phospho-proteomic and metabolic analyses of HER2+ breast cancer  Taro Hitosugi, Ph.D. Mayo Clinic MN Minnesota Affiliate CCR Basic and Translational
A structural framework for targeting the HER3 receptor in breast cancer  Natalia Jura, Ph.D. University of California, San Francisco  CA San Francisco Bay Affiliate CCR Basic and Translational
Cancer mutations and prognosis in premenopausal, early-stage breast cancer  Sherene Loi, Ph.D. The University of Melbourne Australia N/A CCR Basic and Translational
The role of lncRNAs associated with neoadjuvant hormone therapy sensitivity  Christopher Maher, Ph.D. Washington University in St.Louis MO St. Louis Affiliate CCR Basic and Translational
Targeting the APOBEC3B-induced mutator phenotype in breast cancer prevention  Guang Peng, M.D., Ph.D. University of Texas M.D. Anderson Cancer Center TX Houston Affiliate CCR Basic and Translational
Glycosylation as a link between breast cancer metabolism and tumorigenesis  Matthew Pratt, Ph.D. USC/University of Southern California CA Los Angeles County Affiliate CCR Basic and Translational
The role of CAF-derived IGFBP-2 in preventing anoikis in breast cancer cells  Zachary Schafer, Ph.D. University of Notre Dame IN Northern Indiana Affiliate CCR Basic and Translational
Endocrine therapy resistance of ER+ breast cancer caused by ESR1 gene aberrations  Jieya Shao, Ph.D. Washington University in St.Louis MO St. Louis Affiliate CCR Basic and Translational
A nanoparticle-based HER2 breast cancer vaccine  Nicole Steinmetz, Ph.D. Case Western Reserve University OH Northeast Ohio Affiliate CCR Basic and Translational
A novel protein complex controls homologous recombination repair in breast cancer  Jingsong Yuan, M.D., Ph.D. University of Texas M.D. Anderson Cancer Center TX Houston Affiliate CCR Basic and Translational
Therapeutic strategies to restore the immunosurveillance against breast cancer  Xiang Zhang, Ph.D. Baylor College of Medicine TX Houston Affiliate CCR Basic and Translational
Improving how we predict toxicity for older women with breast cancer Rachel Freedman, M.D. Dana-Farber Cancer Institute MA Massachusetts Affiliate CCR Clinical
A trial of endocrine response in patients with invasive lobular carcinoma Rachel Jankowitz, M.D. University of Pittsburgh PA Pittsburgh Affiliate CCR Clinical
Application of lipidomics to a sulindac intervention of pain Jessica Miller, Ph.D. University of Arizona AZ Southern Arizona Affiliate CCR Clinical
Epigenetic memory of breast cancer treatment-induced inflammation and fatigue Mylin Torres, M.D. Emory University GA Greater Atlanta Affiliate CCR Clinical
Susan G. Komen graduate training in breast cancer disparities at UC Berkeley Joan Bloom, Ph.D.; Mahasin Mujahid, Ph.D.  University of California, Berkeley CA San Francisco Bay Affiliate Graduate Training in Disparities Research Grants
Breast cancer disparities among low income women Cathy Bradley, Ph.D. Virginia Commonwealth University VA Central Virginia Affiliate Graduate Training in Disparities Research Grants
Multidisciplinary training in the biology of breast cancer disparities Michele Cote, Ph.D.; Manohar Ratnam, Ph.D. Wayne State University MI Komen Detroit Race for the Cure Graduate Training in Disparities Research Grants
Graduate training program in breast cancer disparities at UTSPH Sally Vernon, Ph.D. University of Texas Health Science Center at Houston TX Houston Affiliate Graduate Training in Disparities Research Grants
UIC Komen breast cancer disparities fellowship Garth Rauscher, Ph.D. University of Illinois - Chicago IL Chicagoland Area Affiliate Graduate Training in Disparities Research Grants
UNC-CIDRZ Proposal to Conduct a Comprehensive Assessment of Current Breast and Cervical Cancer Control in Zambia
Groesbeck Parham The University of North Carolina at Chapel Hill NC North Carolina Triangle to Coast Affiliate GSP
BHGI International Learning Laboratories Benjamin Anderson, M.D. Fred Hutchinson Cancer Research Center WA Puget Sound Affiliate Komen Scholars
Establishing novel therapeutic approaches for breast cancer Alan Ashworth, Ph.D. Institute of Cancer Research Great Britain NA Komen Scholars
Predictive factors of recurrences and distant metastases in ER+ breast cancer Sunil Badve, M.D. Indiana University IN Central Indiana Affiliate Komen Scholars
Profiling of Metastatic Triple Negative Breast Cancer Kimberly Blackwell, M.D. Duke University NC North Carolina Triangle to Coast Affiliate Komen Scholars
Biomechanical profiling as a biomarker for breast cancer progression Gerard Blobe, M.D., Ph.D. Duke University NC North Carolina Triangle to Coast Affiliate Komen Scholars
Breast cancer risk assessment using copy number variation Melissa L. Bondy, Ph.D. Baylor College of Medicine TX Houston Affiliate Komen Scholars
Analysis of the Integration of Cell-Cell Adhesion & Yap Networks Regulating Tumor Growth & Invasion Joan Brugge, Ph.D. Harvard Medical School MA Massachusetts Affiliate Komen Scholars
Translating biology into therapeutic advances Lisa Carey, M.D. University of North Carolina at Chapel Hill NC North Carolina Triangle to Coast Affiliate Komen Scholars
Early phase clinical trials of targeted therapy for metastatic breast cancer Claire Dees, M.D. University of North Carolina at Chapel Hill NC North Carolina Triangle to Coast Affiliate Komen Scholars
Efficacy Of DNA damaging and non-damaging regimens according to molecular subtypes defined on CTCs Angelo DiLeo, M.D., Ph.D. Sandro Pitigliani Medical Oncology Unit Italy Susan G. Komen Italia Komen Scholars
Impact of risk-reducing salpingo-oophorectomy on non-cancer outcomes in high risk women Susan Domchek, M.D. University of Pennsylvania PA Philadelphia Affiliate Komen Scholars
Mechanisms of Endocrine Resistance in Estrogen Receptor Positive Breast Cancer Matthew Ellis, Ph.D. Baylor College of Medicine TX Houston Affiliate Komen Scholars
Development of biomarkers of response to prevention interventions with lignans Carol Fabian, M.D. University of Kansas Medical Center Research Institute KS Greater Kansas City Affiliate
Komen Scholars
Hereditary breast cancer: cause and effect William Foulkes, M.D., Ph.D. McGill University Canada NA Komen Scholars
Stress reduction in breast cancer survivors: intervention development and evaluation Patricia Ganz, M.D. University of California, Los Angeles CA Los Angeles County Affiliate Komen Scholars
Exploratory Study of Immune Cells in Breast Cancer Judy Garber, M.D. Dana-Farber Cancer Institute MA Massachusetts Affiliate Komen Scholars
Predictors of bone metastasis in breast cancer Julie Gralow, M.D. University of Washington School of Medicine Alliance WA Puget Sound Affiliate Komen Scholars
Microenvironmental and epigenomic mechanisms of therapeutic resistance Joe Gray, Ph.D. Oregon Health & Science University OR Oregon and SW Washington Affiliate
Komen Scholars
Muscle Weakness Associated with Breast Cancer Bone Metastases Theresa Guise, M.D. Indiana University IN Central Indiana Affiliate Komen Scholars
Using breast tissue expression patterns to inform our understanding of breast cancer risk factors Susan Hankinson, Sc.D. Brigham and Women's Hospital and Harvard Medical School MA Massachusetts Affiliate Komen Scholars
Biomarker studies for personalized breast cancer care Daniel Hayes, M.D. University of Michigan MI Mid-Michigan Affiliate
Komen Scholars
Reversion of triple-negative breast cancer: insights to new targeted therapy Mien-Chie Hung, Ph.D. UT M.D. Anderson Cancer Center TX Houston Affiliate Komen Scholars
MR imaging phenotypes of breast cancer Nola Hylton, Ph.D. University of California, San Francisco CA San Francisco Bay Affiliate Komen Scholars
Uncovering mechanisms contributing to metastasis and to drug resistance in breast cancer Nancy Hynes, Ph.D. Friedrich Miescher Institute for Biomedical Research Switzerland NA Komen Scholars
Mechanisms of endocrine action: ER-induced apoptosis and HRT-associated breast cancer V. Craig Jordan, Ph.D., D. Sc. UT M.D. Anderson Cancer Center TX Houston Affiliate Komen Scholars
Molecular and clinical characterization of breast cancer heterogeneity in Israel Bella Kaufman, M.D. Chaim Sheba Medical Center Israel NA Komen Scholars
Identification of new genes for inherited breast cancer by application of next generation sequencing in high-risk families Mary-Claire King, Ph.D. University of Washington WA Puget Sound Affiliate Komen Scholars
Elucidating Novel Mechanisms of Resistance to HER2-Directed Therapy Ian Krop, M.D., Ph.D. Dana-Farber Cancer Institute MA Massachusetts Affiliate Komen Scholars
Understanding and targeting IGF's role in G2/M progression Adrian Lee, Ph.D. University of Pittsburgh PA Pittsburgh Affiliate Komen Scholars
Mechanism by which BRCA1 elicits a state of mammary epithelial differentiation control David Livingston, M.D. Dana-Farber Cancer Institute and Harvard Medical School MA Massachusetts Affiliate Komen Scholars
Optimizing Akt/mTOR targeted breast cancer therapy Funda Meric-Bernstam, M.D., Ph.D. UT M.D. Anderson Cancer Center TX Houston Affiliate Komen Scholars
PARP inhibition after pre-operative chemotherapy Kathy Miller, M.D. Indiana University IN Central Indiana Affiliate Komen Scholars
Combinatorial adaptive resistance therapy in breast cancer Gordon Mills, M.D., Ph.D. UT M.D. Anderson Cancer Center TX Houston Affiliate Komen Scholars
Estrogen receptor-positive breast cancer recurrence through dependence receptor pathway Harikrishna Nakshatri, Ph.D., D.V.M. Indiana University IN Central Indiana Affiliate Komen Scholars
Translating Breast Cancer Genomics In The Clinic Olunfunmilayo Olopade, M.D. University of Chicago IL Chicagoland Area Affiliate Komen Scholars
Interplay between SRC-3, TRAF4 and ERK3 in breast cancers Bert O’Malley, M.D. Baylor College of Medicine TX Houston Affiliate Komen Scholars
Biological consequences of novel PTEN pathway signaling defects in breast cancer Ramon Parsons, M.D., Ph.D. Icahn School of Medicine at Mount Sinai NY Greater New York City Affiliate Komen Scholars
Breast cancer in young women Ann Partridge, M.D. Dana-Farber Cancer Institute MA Massachusetts Affiliate Komen Scholars
Identification and education of low-income women at risk for hereditary breast cancer Rena Pasick, Dr.PH. University of California, San Francisco CA San Francisco Bay Affiliate Komen Scholars
Breast cancer cell sensitivity to radiotherapy in the presence of PARP inhibitors Lori Pierce, M.D. University of Michigan MI Mid-Michigan Affiliate Komen Scholars
Triple negative breast cancer: subtypes, molecular targets, and therapeutic approaches Jennifer Pietenpol, Ph.D. Vanderbilt University TN Greater Nashville Affiliate Komen Scholars
Plk2 function in mammary gland development and breast cancer Jeffrey Rosen, Ph.D. Baylor College of Medicine TX Houston Affiliate Komen Scholars
Genomic predictors of chemotherapy-induced toxicity Brian Schneider, M.D. Indiana University IN Central Indiana Affiliate Komen Scholars
Mutational Landscape of Invasive Lobular Breast Cancer Christos Sotiriou, M.D., Ph.D. Jules Bordet Institute Belgium NA Komen Scholars
Overcoming or preventing resistance to HER2 targeted therapies Neil Spector, M.D. Duke University School of Medicine NC North Carolina Triangle to Coast Affiliate Komen Scholars
Phase II study of 5-azacytidine and entinostat (MS-275) in patients with advanced breast cancer  Vered Stearns, M.D. Sidney Kimmel Cancer Center at Johns Hopkins University School of Medicine MD   Komen Scholars
Validation and implementation of genomic testing for chemotherapy and endocrine sensitivity William Symmans, M.D. UT M.D. Anderson Cancer Center TX Houston Affiliate Komen Scholars
Mammary stem cells and breast cancer Geoffrey Wahl, Ph.D. The Salk Institute for Biological Studies CA San Diego Affiliate Komen Scholars
Regulation of metastasis by mitochondrial DNA Daniel Welch, Ph.D. University of Kansas Medical Center Research Institute KS Greater Kansas City Affiliate Komen Scholars
MRI guided preoperative partial breast irradiation in early stage breast cancer Julia White, M.D. Ohio State University OH Columbus Komen Scholars
Johns Hopkins breast cancer program longitudinal repository Antonio Wolff, M.D. Johns Hopkins University MD   Komen Scholars
Identifying translational regulated genes activated by insulin-like growth factor signaling Douglas Yee, M.D. University of Minnesota, Masonic Cancer Center MN Minnesota Affiliate Komen Scholars
Carolina Breast Cancer Study Shelton Earp, M.D.; Shelley Hwang, M.D. University of North Carolina at Chapel Hill NC North Carolina Triangle to Coast Affiliate Opportunity Grants
Randomized phase II trial of neoadjuvant cisplatin vs doxorubicin/ cyclophosphamide (“AC”) in women with newly diagnosed breast cancer and germline BRCA mutation Nadine Tung, M.D.; Judy Garber, M.D. Dana-Farber Cancer Institute MA Massachusetts Affiliate Opportunity Grants
Investigation of ILF2 as a novel breast cancer therapeutic target Jessica Bockhorn, Ph.D.; Mark Pegram, M.D. (Mentor) Stanford University CA San Francisco Bay Affiliate PDF Basic and Translational
Targeting the cell cycle in sporadic & BRCA mutant triple negative breast cancer Jason Carey, Ph.D.; Khandan Keyomarsi, Ph.D. (Mentor) Unviersity of Texas M.D. Anderson TX Houston Affiliate PDF Basic and Translational
Targeting metabolic pathways to circumvent endocrine resistance in breast cancer Subhamoy Dasgupta, Ph.D.; Bert O'Malley, M.D. (Mentor) Baylor College of Medicine TX Houston Affiliate PDF Basic and Translational
Determining mechanisms of RON kinase signaling in breast cancer metastasis Najme Faham, Ph.D.; Alana Welm, Ph.D. (Mentor) Oklahoma Medical Research Foundation OK Oklahoma City PDF Basic and Translational
Determining the role of somatic mutations in SERM-resistant breast cancers Sean Fanning, Ph.D.; Geoffrey Greene, Ph.D. (Mentor) University of Chicago IL Chicagoland Area Affiliate PDF Basic and Translational
Global cell characterization of the BRCA1 interactome using the NEDDylator Sean Hudson, Ph.D.; James Wells, Ph.D. (Mentor) University of California, San Francisco CA San Francisco Bay Affiliate PDF Basic and Translational
Radiographic-histological correlates of dense breast tissue Brad Keller, Ph.D.; Despina Kontos, Ph.D. (Mentor) Michael Feldman, M.D., Ph.D. (Co-Mentor) University of Pennsylvania PA Philadelphia Affiliate PDF Basic and Translational
Interrogating the function of the oncogene TLOC1 in breast cancer Ji Li, Ph.D.; William Hahn, M.D., Ph.D. (Mentor) Dana-Farber Cancer Institute MA Massachusetts Affiliate PDF Basic and Translational
Mechanism of PARP inhibitor in breast cancer therapy Mo Li, Ph.D.; Xiaochun Yu, M.D., Ph.D. (Mentor) The University of Michigan MI Mid-Michigan Affiliate PDF Basic and Translational
How does Loss of the INPP4B affect breast cancer etiology and treatment outcomes? Hui Liu, Ph.D.; Gerburg Wulf, M.D., Ph.D. (Mentor); Lewis Cantley, Ph.D. (Co-Mentor) Beth Israel Deaconess Medical Center MA Massachusetts Affiliate PDF Basic and Translational
Novel anti-metastamiR therapy for metastatic breast cancer Rebecca Marquez, Ph.D.; Liang Xu, M.D., Ph.D. (Mentor); Danny Welch, Ph.D. (Co-Mentor) University of Kansas Center for Research KS Greater Kansas City Affiliate PDF Basic and Translational
Translating lobular breast cancer ‘omics’ to improved patients outcome Otto Metzger, M.D.; Eric Winer, M.D. (Mentor) Dana-Farber Cancer Institute MA Massachusetts Affiliate PDF Basic and Translational
A novel therapeutic and diagnostic target in triple negative breast cancers Krishna Midde, Ph.D.; Pradipta Ghosh, M.D. (Mentor); Marilyn Farquhar, Ph.D. (Co-Mentor) University of California, San Diego CA San Diego Affiliate PDF Basic and Translational
Targeting DNA damage responses in breast cancer Kareem Mohni, Ph.D.; David Cortez, Ph.D. (Mentor) Vanderbilt University Medical Center TN Greater Nashville Affiliate PDF Basic and Translational
LTBP1: A prometastatic factor linking pregnancy to breast cancer Carrie Oliver, Ph.D.; Pamela Cowin, Ph.D. (Mentor) New York University School of Medicine NY Greater New York City Affiliate PDF Basic and Translational
Development of selective Grp94 inhibitors for the treatment of breast cancer Hardik Patel, Ph.D.; Gabriela Chiosis, Ph.D. (Mentor); Shanu Modi, M.D. (Co-Mentor) Memorial Sloan-Kettering Cancer Center NY Greater New York City Affiliate PDF Basic and Translational
Drivers and therapeutic targets in mucinous carcinomas of the breast Salvatore Piscuoglio, Ph.D.; Britta Weigelt, Ph.D. (Mentor) Memorial Sloan-Kettering Cancer Center NY Greater New York City Affiliate PDF Basic and Translational
Improving response to radio and chemotherapy in triple-negative breast cancer Giorgio Seano, Ph.D.; Rakesh Jain, Ph.D. (Mentor) Massachusetts General Hospital MA Massachusetts Affiliate PDF Basic and Translational
BET bromodomain proteins as novel therapeutic targets in TNBC Shaokun Shu, Ph.D.; Kornelia Polyak, M.D., Ph.D. (Mentor) Dana-Farber Cancer Institute MA Massachusetts Affiliate PDF Basic and Translational
Harnessing altered ER turnover in invasive lobular carcinoma for improved therapy Sreeja Sreekumar, Ph.D.; Steffi Oesterreich, Ph.D. (Mentor) University of Pittsburgh PA Pittsburgh Affiliate PDF Basic and Translational
Tracking intratumor heterogeneity in triple negative breast cancer Daniel Stover, M.D.; Joan Brugge, Ph.D. (Mentor); Eric Winer, M.D. (Co-Mentor) Harvard Medical School MA Massachusetts Affiliate PDF Basic and Translational
Re-targeting virus-specific CD8+ T cells to recognize and attack breast tumors Kwame Twumasi-Boateng, Ph.D.; Brad Nelson, Ph.D. (Mentor) British Columbia Cancer Agency Branch Canada   PDF Basic and Translational
Optimization of calcification imaging in digital breast tomosynthesis Raymond Acciavatti, Ph.D.; Emily Conant, M.D. (Mentor); Andrew Maidment, Ph.D. (Co-Mentor)  University of Pennsylvania PA Philadelphia Affiliate PDF Clinical
Identification of phosphatases for the treatment of ER-negative breast cancer Powel Brown, M.D., Ph.D. UT MD Anderson   TX Houston Affiliate SAB Grants
Increasing Access of Latinas into Breast Cancer Clinical Trials Amelie Ramirez, Ph.D. UT Health Science Center at San Antonio TX San Antonio Affiliate SAB Grants
Examination of the human kinome for novel genome-specific therapeutic targets in triple-negative breast cancer (TNBC) George Sledge, M.D. Stanford University CA San Francisco Bay Affiliate SAB Grants
Clinical trials for HER2+ breast cancer Eric Winer, M.D. Dana-Farber Cancer Institute MA Massachusetts Affiliate SAB Grants
Scientific travel award for breast cancer researcher to attend Obesity Society’s Annual Scientific Meeting 2013 Derek Huffman, Ph.D. Obesity Week, LLC     SPP
2014 Accelerating Anticancer Agent Development and Validation Workshop H. Kim Lyerly, M.D. Duke University NC North Carolina Triangle to Coast Affiliate SPP
Evidence Based Consensus Conference on Margins in DCIS Treated With and Without Radiotherapy Monica Morrow, M.D. Society of Surgical Oncology     SPP
Advocates in Science Educational Program at ASCO Breast Cancer Symposium 2014 Elda Railey Research Advocacy Network     SPP
Conference Sponsorship for AACR FY14 Programming Michael Stewart American Association for Cancer Research (AACR)      SPP
2014 AACR Annual Meeting Michael Stewart American Association for Cancer Research (AACR)      SPP
IMPAKT 2014 Nikolaj Tomma European Society for Medical Oncology     SPP
Breast Cancer in Young Women (BCY2) Conference 2014 – Dublin, Ireland  Roberta Ventura European School of Oncology     SPP
Society of Surgical Oncology 67th Annual Cancer Symposium Eileen Widmer Society of Surgical Oncology     SPP