Anti-Müllerian Hormone (AMH) Levels
Anti-Müllerian hormone (AMH) is produced in the ovaries. It’s important in the development of reproductive organs. It is a marker of ovarian reserve (the number of eggs a woman has left in her ovaries), which helps show a woman’s fertility potential.
Blood levels of AMH peak around age 20-25, then decline as a woman gets closer to menopause . After menopause, AMH is no longer detectable .
Premenopausal women with higher blood levels of AMH may have a higher risk of breast cancer compared to women of the same age who have lower levels of AMH [25-28].
Why might AMH blood levels be related to breast cancer risk?
Higher AMH levels may reflect some reproductive events. For example, premenopausal women with higher blood levels of AMH at a given age are more likely to have a later age at menopause than those with lower AMH levels .
Having a later age at menopause is linked to an increased risk of breast cancer [9,14,19]. This increased risk is likely due, at least in part, to the amount of estrogen a woman is exposed to in her life. A higher lifetime exposure to estrogen is related to an increased breast cancer risk .