Anti-Müllerian hormone (AMH) levels

Anti-Müllerian hormone (AMH) is produced in the ovaries. It’s important in the development of reproductive organs.

Blood levels of AMH peak around age 20-25, then decline as a woman gets closer to menopause [389]. After menopause, AMH is no longer detectable [389].

Women with higher blood levels of AMH may have a higher risk of breast cancer compared to women of the same age who have lower levels of AMH [389-392].

Why might AMH blood levels be related to breast cancer risk?

Higher AMH levels may reflect some reproductive events. For example, women with higher blood levels of AMH are more likely to have a later age at menopause than women with lower AMH levels [393].

Having a later age at menopause is linked to an increased risk of breast cancer [10,15,20]. This increased risk is likely due, at least in part, to the amount of estrogen a woman is exposed to in her life. A higher lifetime exposure to estrogen is related to an increase in breast cancer risk [19].

Updated 02/25/21