Side Effects of Tamoxifen
Tamoxifen can be used to:
- Treat hormone receptor-positive early and locally advanced breast cancers (learn more)
- Treat hormone receptor-positive metastatic breast cancers (learn more)
- Lower the risk of breast cancer for women at high risk of breast cancer who haven’t been diagnosed (learn more)
Tamoxifen can be used to treat breast cancers in women and men.
Tamoxifen has fewer side effects than chemotherapy. For example, tamoxifen doesn’t cause nausea.
Side effects in women
Menopausal symptoms, such as hot flashes, are common in women who take tamoxifen [102].
Although menopausal symptoms may become less frequent and less intense over time, they can still be hard to manage. If you have symptoms, talk with your health care provider about ways to treat them.
The most serious health risks of tamoxifen, such as endometrial cancer (cancer of the lining of the uterus) and blood clots in the lungs, are rare [102].
The table below lists some possible side effects and health risks of tamoxifen in women.
Side effects and health risks of tamoxifen in women | |
Common |
|
Rare |
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Adapted from Rimawi MF and Osborne CK [102]. |
Before you begin taking tamoxifen, talk with your health care provider about possible side effects and how to manage them.
Side effects in men
The table below lists some possible side effects and health risks of tamoxifen in men.
Side effects and health risks of tamoxifen in men | |
Common |
|
Rare |
|
Adapted from select sources [102-104]. |
Before you begin taking tamoxifen, talk with your health care provider about possible side effects and how to manage them.
Side effects of tamoxifen versus side effects of aromatase inhibitors
Although both aromatase inhibitors and tamoxifen can cause menopausal symptoms, such as hot flashes, many of their side effects differ.
Learn about how the side effects of these hormone therapies compare.
Susan G. Komen® Support Resources |
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Updated 07/04/23