The Who, What, Where, When and Sometimes, Why.

Hair dyes and breast cancer risk

This summary table contains detailed information about research studies. Summary tables are a useful way to look at the science behind many breast cancer guidelines and recommendations. However, to get the most out of the tables, it’s important to understand some key concepts. Learn how to read a research table.

Introduction: Research studies show the use of permanent hair dye does not increase the risk of breast cancer.

Prospective cohort studies and a meta-analysis of 14 studies have found no link between hair dye and breast cancer risk.

Learn more about hair dyes, hair relaxers and breast cancer risk.

Learn about the strengths and weaknesses of different types of studies.

See how this risk factor compares with other risk factors for breast cancer.

Study selection criteria: Prospective cohort studies and meta-analyses.

Table note: Relative risk above 1 indicates increased risk. Relative risk below 1 indicates decreased risk.

Study

Study Population
(number of participants)

Follow-up
(years)

Relative Risk of Breast Cancer in Women who Ever Used Hair Dye Compared to Those who Never Used Hair Dye,
RR (95% CI)

Prospective cohort studies

Nurses’ Health Study [1]

117,200
(9,252 cases)

36

1.02 (0.98-1.07)

Cancer Prevention Study II (CPS-II) [2]

573,369
(number of cases not given)

7

0.95 (0.83-1.08)

Sister Study [3]

46,709
(2,794 cases)*

8

1.09 (1.01-1.17)

Shanghai Women’s Health Study [4]

73,366
(592 cases)

7

0.93 (0.78-1.09)

Meta-analyses

Takkouche et al. [5]

14 studies including 680,633 women
(any hair dye use)

 

1.06 (0.95-1.18)

 

9 studies
(permanent hair dye use only)

 

0.98 (0.91-1.07)

 

9 studies
(intensive hair dye use)

 

0.99 (0.89-1.11)

NS = Not statistically significant

* All participants have a sister who diagnosed with breast cancer.

References

  1. Zhang Y, Birmann BM, Han J, et al. Personal use of permanent hair dyes and cancer risk and mortality in US women: prospective cohort study. BMJ. 370:m2942, 2020.
  2. Thun MJ, Altekruse SF, Namboodiri MM, et al. Hair dye use and risk of fatal cancer in U.S. women. J Natl Cancer Inst. 86(3):210-215, 1994.
  3. Eberle CE, Sandler DP, Taylor KW, White AJ. Hair dye and chemical straightener use and breast cancer risk in a large US population of black and white women. Int J Cancer. 147(2):383-391, 2020.
  4. Mendelsohn JB, Li QZ, Ji BT, et al. Personal use of hair dye and cancer risk in a prospective cohort of Chinese women. Cancer Sci. 100(6):1088-91, 2009.
  5. Takkouche B, Etminan M, Montes-Martinez A. Personal use of hair dyes and risk of cancer: a meta-analysis. JAMA. 293(20):2516-25, 2005.

Updated 12/29/20

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