Research Table Topics

Risk Factors

Established and Probable

Age at menopause and breast cancer risk

Alcohol and breast cancer risk

Birth control pills and breast cancer risk

Birthweight and breast cancer risk

Blood androgen levels and breast cancer risk

Blood estrogen levels and breast cancer risk

Body weight and breast cancer risk

BRCA1 and BRCA2 inherited gene mutations and cancer risk

Breastfeeding and breast cancer risk

Carotenoids and breast cancer risk

Exercise (physical activity) and breast cancer risk

Fruits and vegetables and breast cancer risk

Hyperplasia and breast cancer risk

IGF-1 and breast cancer risk

Light at night/shift work and breast cancer risk

Menopausal hormone therapy and breast cancer risk

Prolactin and breast cancer risk

Weight gain and breast cancer risk

Factors Under Study  

Dairy products and breast cancer risk

Dietary fat and breast cancer risk

Meat consumption and breast cancer risk

Secondhand smoke and breast cancer risk

Smoking and breast cancer risk

Soy and breast cancer risk

Vitamin D and breast cancer risk

Factors Not Related to Breast Cancer 

Abortion and breast cancer risk

Blood organochlorine levels and breast cancer risk

Breast implants and breast cancer risk

Electromagnetic fields and breast cancer risk

Hair dyes and breast cancer risk

Risk-Lowering Drugs (Chemoprevention)

Tamoxifen and raloxifene to reduce breast cancer risk

Early Detection and Screening

Mammography

Mammography screening for women 40-49

Mammography screening for women 50-69

3D mammography (breast tomosynthesis) and breast cancer screening

Digital vs. film mammography screening

Breast MRI

Breast MRI for women at high risk

Diagnosis and Prognostic Factors

Estrogen receptor status and overall survival

Accuracy of sentinel node biopsy

Treatment

Ductal carcinoma in situ (DCIS)

Lumpectomy plus radiation therapy for DCIS

Tamoxifen for DCIS

Early and locally advanced breast cancer

Mastectomy versus lumpectomy plus radiation therapy

Radiation therapy after mastectomy for invasive breast cancer

Chemotherapy for early breast cancer

Chemotherapy combinations for early breast cancer

Neoadjuvant chemotherapy for invasive breast cancer

Tamoxifen for early breast cancer

Aromatase inhibitors for early breast cancer

Neoadjuvant hormone therapy for estrogen receptor-positive breast cancer

Trastuzumab (Herceptin) for early breast cancer

Inflammatory breast cancer (non-metastatic)

Treatment for inflammatory breast cancer and overall survival

Metastatic breast cancer

CDK4/6 inhibitors for treatment of metastatic breast cancer

Trastuzumab (Herceptin) for treatment of metastatic breast cancer

Pertuzumab (Perjeta) for treatment of metastatic breast cancer

Lapatinib (Tykerb) for treatment of metastatic breast cancer

High-dose chemotherapy (bone marrow transplant)

Support

Social support and breast cancer survival

Support groups and breast cancer survival

Survivorship Topics

Breast cancer survival

Alcohol and breast cancer survival

Body weight and breast cancer survival

Pregnancy and breast cancer survival

Menopausal hormone therapy and breast cancer recurrence

Physical activity (exercise) and breast cancer survival

Smoking and breast cancer survival

Total fat intake and breast cancer survival

Easing menopausal symptoms

Acupuncture for menopausal symptoms

Anti-depressants and other non-hormone medications for menopausal symptoms

Black cohosh and relief of menopausal symptoms

Soy and relief of menopausal symptoms

Supplements and relief of menopausal symptoms