Research Table Topics

Established and Probable Risk Factors

Age at menopause and breast cancer risk

Alcohol and breast cancer risk

Birth control pills and breast cancer risk

Birthweight and breast cancer risk

Blood androgen levels and breast cancer risk

Blood estrogen levels and breast cancer risk

Body weight and breast cancer risk

BRCA1 and BRCA2 inherited gene mutations and cancer risk

Breastfeeding and breast cancer risk

Carotenoids and breast cancer risk

Exercise (physical activity) and breast cancer risk

Fruits and vegetables and breast cancer risk

Hyperplasia and breast cancer risk

IGF-1 and breast cancer risk

Light at night/shift work and breast cancer risk

Menopausal hormone therapy and breast cancer risk

Prolactin and breast cancer risk

Smoking and breast cancer risk

Weight gain and breast cancer risk

Factors Under Study

Dairy products and breast cancer risk

Dietary fat and breast cancer risk

Hair dyes and breast cancer risk

Meat consumption and breast cancer risk

Secondhand smoke and breast cancer risk

Soy and breast cancer risk

Vitamin D and breast cancer risk

Factors Not Related to Breast Cancer

Abortion and breast cancer risk

Blood organochlorine levels and breast cancer risk

Breast implants and breast cancer risk

Electromagnetic fields and breast cancer risk

Tamoxifen and raloxifene to reduce breast cancer risk

Mammography

Screening mammography for women 40-49

Screening mammography for women 50-69

3D mammography (breast tomosynthesis) and breast cancer screening

Breast MRI

Breast MRI for women at high risk

Estrogen receptor status and overall survival

Accuracy of sentinel node biopsy

Ductal carcinoma in situ (DCIS)

Lumpectomy plus radiation therapy for DCIS

Tamoxifen for DCIS

Early and locally advanced breast cancer

Mastectomy versus lumpectomy plus radiation therapy

Radiation therapy after mastectomy for invasive breast cancer

Chemotherapy for early breast cancer

Chemotherapy combinations for early breast cancer

Neoadjuvant chemotherapy for invasive breast cancer

Tamoxifen for early breast cancer

Aromatase inhibitors for early breast cancer

Neoadjuvant hormone therapy for estrogen receptor-positive breast cancer

Trastuzumab (Herceptin) for early breast cancer

Inflammatory breast cancer (non-metastatic)

Treatment for inflammatory breast cancer and overall survival

Metastatic breast cancer

CDK4/6 inhibitors and treatment for metastatic breast cancer

Trastuzumab (Herceptin) and treatment for metastatic breast cancer

Trastuzumab deruxtecan (Enhertu) and treatment for metastatic breast cancer

Pertuzumab (Perjeta) and treatment for metastatic breast cancer

Tucatinib (Tukysa) and treatment for metastatic breast cancer

Lapatinib (Tykerb) and treatment for metastatic breast cancer

PARP Inhibitors and treatment for metastatic breast cancer

Pembrolizumab (Keytruda) and treatment for metastatic breast cancer

Sacituzumab govitecan (Trodelvy) for treatment of metastatic breast cancer

High-dose chemotherapy (bone marrow transplant)

Social support and breast cancer survival

Support groups and breast cancer survival

Alcohol and breast cancer survival

Body weight and breast cancer survival

Having a child after breast cancer treatment and survival

Menopausal hormone therapy and breast cancer recurrence

Physical activity (exercise) and breast cancer survival

Smoking and breast cancer survival

Total fat intake and breast cancer survival

Acupuncture for relief of menopausal symptoms

Anti-depressants and other non-hormone medications for relief of menopausal symptoms

Black cohosh for relief of menopausal symptoms

Soy for relief of menopausal symptoms

Supplements for relief of menopausal symptoms

Updated 04/19/23