The Who, What, Where, When and Sometimes, Why.

What is a Pathology Report

The pathology report

The breast tissue removed during a biopsy is sent to a pathologist. A pathologist is the physician who looks at the tissue under a microscope and determines whether or not the tissue contains cancer.

The pathologist prepares a report of the findings, including the diagnosis, and sends it to the ordering physician (either your surgeon or your oncologist).

When needed, the pathologist does more tests on the tissue sample. These results may be written in separate reports. So, you may get more than one report for the same biopsy.

Along with other test results and any X-rays or other imaging, the pathology report(s) informs your diagnosis, prognosis and treatment.

Ideally, a medical team that includes your oncologist, radiologist, surgeon and pathologist will plan your treatment.

Findings on a pathology report

Your pathology report contains the information that describes your diagnosis.

Try not to focus on any one item in the report since it’s the sum of all the information that’s most important to your prognosis and treatment.

Pathology reports are written in medical language because they are prepared for doctors. This can make some of the wording hard to understand.

Your physician (either your surgeon or your oncologist) will go over the main findings of the report with you and answer any questions you may have.

Find questions to ask your doctor concerning your pathology results.

Learn about the contents of a pathology report.

Get a copy of your pathology report

Ask for a copy of your pathology report for your medical records.

It can be hard to take in all the findings at once. It’s helpful to have a copy of the report you can refer to later.

Experience of the pathologist and pathology laboratory

An accurate diagnosis leads to the most effective treatment possible. So, the skill of your pathologist is important. You want to make sure your tissue sample(s) is handled properly and diagnosed correctly.

One way to do this is to ask your doctor about the experience of the pathologist and the pathology lab.

Below are some questions you may want to ask before your biopsy.

  • Who will evaluate my biopsy sample?
  • How much experience does the pathologist have with breast cancer?
  • How much experience does the pathology lab have with breast cancer?
  • How long will it take to get the results from the pathology lab?

It’s always OK to get a second opinion on your tissue sample(s) from another pathologist.

Preserving your biopsy tissue

It’s standard for hospitals in the U.S. to preserve and store all biopsy samples as formalin fixed paraffin embedded tissue.

When a sample arrives at the pathology lab, it’s treated with a substance called formalin, which keeps it from breaking down over time.

The treated sample is embedded in a block of paraffin (wax).

If you wish to have your biopsy tissue re-examined for a second opinion, or if a new test becomes available that could affect your treatment, the preserved tissue can be obtained from the hospital where the biopsy was done.

Learn more about preserving breast cancer tissue for pathology.

Second opinions

Second opinions can be useful in getting the most accurate diagnosis possible.

They are especially useful in getting an accurate diagnosis for rare types of cancers (such as metaplastic breast cancer) that are hard to diagnose.

It’s always OK to get a second opinion before your biopsy or after, when you have the results.

Most health plans will allow you to get a second opinion, as long as the second doctor is a member of your health plan.

Learn more about getting a second opinion.

What’s not in a pathology report

Stage/pathologic stage and clinical stage

Breast cancer stage is not always listed in pathology reports because it’s derived from the results of the biopsy of the tumor tissue, any biopsies of the lymph nodes and other tests. These biopsies and some pathology tests may not be done at the same time.

Thus, you may have more than one report that gives information on staging.

Your medical team combines all the pathology information with any scans (to check for spread to other parts of the body) and determines the breast cancer stage.

Breast cancer stage is determined by:

Oncotype DX® score is part of breast cancer staging for some estrogen receptor-positive, lymph node-negative tumors.

Learn more about breast cancer staging.  

Updated 12/11/20