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Spotlight on Clinical Trials

You're Not Too Young, Bestie

Shining a Spotlight on Patient Advocate Involvement at SABCS

Research

When patient advocates attend major conferences like the San Antonio Breast Cancer Symposium (SABCS), they help shape breast cancer clinical trials by sharing what patients really experience and need when it comes to research. They also help to translate complex science into clear, understandable information that helps patients make informed choices. That’s why patient advocate involvement is so important for improving clinical trials for patients.  In this installment of Spotlight on Clinical Trials, we explore just a few of the many ways that advocates help shape clinical trials and make a […]

Breast Cancer Breakthroughs Episode 18: Right-Sizing Breast Cancer Treatment Through Dose Optimization 

Research

Breakthroughs in breast cancer don’t always mean the development of new drugs – they’re also made by optimizing currently available treatments. Researchers are re-examining some breast cancer treatments through dose optimization.   Maximum tolerated dose (MTD) has been the status quo in breast cancer treatment. Clinical trials determine the MTD by finding the highest drug or treatment amount (dose) with acceptable or tolerable side effects for participants. However, some individuals receiving treatments at MTD still experience significant […]

Susan G. Komen-Led Research Spotlighted at SABCS 2025 

Research

Susan G. Komen-led research was spotlighted at the 2025 San Antonio Breast Cancer Symposium (SABCS) held this week. This is the world’s largest breast cancer conference, and Komen was honored to contribute to the discussion by presenting pivotal work aimed at addressing needs within the breast cancer community.    ASSESS: A Personalized Early Breast Cancer Treatment […]

Honoring Excellence in Breast Cancer Research, Treatment and Advocacy: Meet the 2025 Susan G. Komen Award Recipients 

Research

Susan G. Komen® recently honored five exceptional individuals for their pivotal roles in advancing breast cancer research, treatment and advocacy. The Brinker Awards, Rising Star Researcher Award and the Research Advocacy Champion Award are some of Komen’s highest distinctions, celebrating trailblazers who are driving lifesaving progress and elevating patient care.   Established in 1992, Susan G. […]

Improving Global Outcomes with the Breast Cancer Care Quality Index (BCCQI) 

Research

The vision of Susan G. Komen is to achieve a world without breast cancer, but with a rising incidence, someone around the world is diagnosed every 14 seconds. Breast cancer is rapidly becoming a global health crisis.   Today, breast cancer is the most common cancer among women worldwide. About 2.3 million new cases and more […]

Breast Cancer Breakthroughs Episode 16: On the Horizon of PI3K Pathway Inhibition

Research

Around 40% of breast cancers, especially those that are hormone receptor-positive (HR+) and HER2-negative (HER2-), begin with a change or mutation in the PIK3CA gene. This mutation happens only in cancer cells and not in healthy cells. Like a switch stuck in the “on” position, a PIK3CA mutation signals cancer cells to keep growing, even […]

Breast Cancer Breakthroughs Episode 15: A Window into Breast Cancer Through a Blood Test 

Research

A liquid biopsy is an innovative tool that provides insight into breast cancer without the need for surgery or traditional needle biopsies. As cancer cells die, they release tiny fragments of their DNA into the bloodstream, known as circulating tumor DNA (ctDNA). In many ways, ctDNA acts like a window into breast cancer, helping guide […]

Breast Cancer Breakthroughs Episode 14: Highlights from ASCO 2025 

Research

The 2025 ASCO Annual Meeting highlighted several groundbreaking developments across the landscape of breast cancer research, from early detection to cutting-edge treatments. These advances offer hope to individuals diagnosed at every stage of breast cancer, from early-stage disease to metastatic breast cancer (MBC).  In this episode of Breast Cancer Breakthroughs, we speak with Dawn Hershman, […]

Breast Cancer Breakthroughs Episode 13 — Unlocking the Potential of Immunotherapy in TNBC 

Research

Immunotherapy is quickly becoming a buzzword in breast cancer research, as it has the potential to revolutionize how some patients are treated. In this episode of Breast Cancer Breakthroughs, we speak with Komen Scholar Melinda Telli, M.D., and Stephanie Graff, M.D., about how immunotherapy works, and we explore the groundbreaking clinical trials in which researchers […]

Understanding Immunotherapy for Breast Cancer  

Research

As scientists learn more about the biology of breast cancer, treatments are increasingly being tailored to the individual and becoming more personalized. This shift to personalized medicine has resulted in many new targeted therapies, including immunotherapy. Today, immunotherapy is quickly becoming one of the most exciting areas of breast cancer research.  Immunotherapy is an innovative, […]

Know Your Risk: How to Use Risk Assessment Tools to Take Charge of Your Breast Health 

Research

Knowing your personal risk of breast cancer can be lifesaving, but what does “risk” really mean? Risk is the chance that something can happen, and in this case, it’s the chance that you may develop breast cancer in your lifetime. While everyone has some level of risk, some people, due to their genetics, family history […]

Beaker bottles with pink liquid

Komen Invests in the Future of Breast Cancer Research 

Research

Supporting Those Who Support the Cause  Susan G. Komen invests in the future of breast cancer research by announcing its latest slate of breast cancer research grants. Since 1982, Komen has invested over $1 billion dollars in breast cancer research. These new grants further cement Komen’s role in funding scientific discoveries and driving breakthroughs that […]

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