Research
Susan G. Komen-led research was spotlighted at the 2025 San Antonio Breast Cancer Symposium (SABCS) held this week. This is the world’s largest breast cancer conference, and Komen was honored to contribute to the discussion by presenting pivotal work aimed at addressing needs within the breast cancer community. ASSESS: A Personalized Early Breast Cancer Treatment […]
Susan G. Komen® recently honored five exceptional individuals for their pivotal roles in advancing breast cancer research, treatment and advocacy. The Brinker Awards, Rising Star Researcher Award and the Research Advocacy Champion Award are some of Komen’s highest distinctions, celebrating trailblazers who are driving lifesaving progress and elevating patient care. Established in 1992, Susan G. […]
The vision of Susan G. Komen is to achieve a world without breast cancer, but with a rising incidence, someone around the world is diagnosed every 14 seconds. Breast cancer is rapidly becoming a global health crisis. Today, breast cancer is the most common cancer among women worldwide. About 2.3 million new cases and more […]
Around 40% of breast cancers, especially those that are hormone receptor-positive (HR+) and HER2-negative (HER2-), begin with a change or mutation in the PIK3CA gene. This mutation happens only in cancer cells and not in healthy cells. Like a switch stuck in the “on” position, a PIK3CA mutation signals cancer cells to keep growing, even […]
A liquid biopsy is an innovative tool that provides insight into breast cancer without the need for surgery or traditional needle biopsies. As cancer cells die, they release tiny fragments of their DNA into the bloodstream, known as circulating tumor DNA (ctDNA). In many ways, ctDNA acts like a window into breast cancer, helping guide […]
The 2025 ASCO Annual Meeting highlighted several groundbreaking developments across the landscape of breast cancer research, from early detection to cutting-edge treatments. These advances offer hope to individuals diagnosed at every stage of breast cancer, from early-stage disease to metastatic breast cancer (MBC). In this episode of Breast Cancer Breakthroughs, we speak with Dawn Hershman, […]
Immunotherapy is quickly becoming a buzzword in breast cancer research, as it has the potential to revolutionize how some patients are treated. In this episode of Breast Cancer Breakthroughs, we speak with Komen Scholar Melinda Telli, M.D., and Stephanie Graff, M.D., about how immunotherapy works, and we explore the groundbreaking clinical trials in which researchers […]
As scientists learn more about the biology of breast cancer, treatments are increasingly being tailored to the individual and becoming more personalized. This shift to personalized medicine has resulted in many new targeted therapies, including immunotherapy. Today, immunotherapy is quickly becoming one of the most exciting areas of breast cancer research. Immunotherapy is an innovative, […]
Knowing your personal risk of breast cancer can be lifesaving, but what does “risk” really mean? Risk is the chance that something can happen, and in this case, it’s the chance that you may develop breast cancer in your lifetime. While everyone has some level of risk, some people, due to their genetics, family history […]
Supporting Those Who Support the Cause Susan G. Komen invests in the future of breast cancer research by announcing its latest slate of breast cancer research grants. Since 1982, Komen has invested over $1 billion dollars in breast cancer research. These new grants further cement Komen’s role in funding scientific discoveries and driving breakthroughs that […]
Big advancements were announced across the board at the 2025 American Society of Clinical Oncology (ASCO) meeting. Phase 3 randomized clinical trials test how well a new therapy compares to the current standard of care, and results from these studies have the potential to change how breast cancer is treated. There were five presentations of […]
Meet the research and advocate experts helping to guide the future of breast cancer research and patient care. As we look ahead to a new fiscal year at Komen, we are proud to welcome new members to our Scientific Advisory Board (SAB) and the Advocates in Science (AIS) Steering Committee. These trusted advisors and advocates […]
