BRCA1 and BRCA2 are the most well known genes linked to breast cancer. People who have a BRCA1 or BRCA2 inherited gene mutation have an increased risk of breast cancer. However, having a BRCA1 or BRCA2 mutation does not mean a person will develop breast cancer.

Several other genes related to breast cancer have been identified. Inherited mutations in genes that increase the risk of breast cancer include ATM, BARD1, CDH1, CHEK2, NF1, PALB2, PTEN, RAD51C, RAD51D, STK11 and TP53.

Only 5 to 10 percent of breast cancers in the U.S. are due to inherited genetic mutations. Most breast cancers are not related to an inherited gene mutation.

Genetic testing gives people the chance to learn if their breast cancer or family history of breast cancer is due to an inherited gene mutation. It’s only recommended for certain people with a high risk of having an inherited gene mutation related to breast cancer.

The decision to have genetic testing should be made with a genetic counselor or a trained health care provider. They can help you determine whether genetic testing would give you useful information about you and your family’s risk of breast and other cancers.

A genetic counselor can discuss the benefits and risks of genetic testing for you. They can also explain the process and help translate complex medical and scientific information into practical knowledge.

Susan G. Komen’s Breast Care Helpline, 1-877 GO KOMEN (1-877-465-6636) provides free, professional support services to anyone with breast cancer questions or concerns Monday through Friday from 9:00 a.m. to 10:00 p.m. ET, or by email at helpline@komen.org.